Demographics Distribution

This report displays the Demographic characteristics for a clinical study. It accomplishes this using both a graphical histogram display (Demographic Details) and a tabular display (Demographic Tables). Optionally, but not by default, it can display statistical comparisons as well.

Report Description

Running this report with the Nicardipine sample setting generates the output shown below. Note: Default settings are used for all options except for the Perform treatment comparison analysis for demographic variables option. This option, which is unchecked by default, is checked in this example.

The Demographics Distribution report initially shows two sections Demographic Characteristics and Distributions.

Distribution and Box PLots

Presents histograms for available demographic characteristics such as age, treatment, sex, race, and country, by default. Click in the Options panel to add additional histograms.

This section contains the following elements:

• One or more Histograms.

The height (or length) of each bar is an indication of the number of subjects exhibiting each demographic characteristic.

You can change how your data are presented in the histograms using the Histogram Options, which can be viewed by clicking for each set of histograms and selecting Display Options.

Quantiles and summary statistics are provided for continuous variables like Age, and frequencies are provided for categorical variables like Sex. These can be viewed by clicking for each set of histograms and selecting Display Options.

 

See Distribution for more information.

Quantiles and summary statistics are provided for continuous variables like Age, and frequencies are provided for categorical variables like Sex. These can be viewed by clicking for each set of histograms and selecting Display Options.

Demographics Characteristics

Presents tables showing how the subject cohort breaks down by sex, race, and country by treatment group and age.

Map

Displays a map showing the countries where the study subjects are located.

Treatment Comparisons

This report performs aone-way ANOVA (analysis of variance) to detect statistical differences for continuous demographic variables (e.g. Age) and contingency analyses for character/categorical variables (e.g. sex, race, and study site) by the treatment variable specified in the Optionspanel.

The One-way Plot above shows the distribution subjects by age for each of the two treatment arms. The analysis statistics are listed in the tables below the plot.

The Mosaic Plots for sex and race by treatment arm are graphical representation of a two-way frequency table or contingency table (shown below their respective plots) , divided into colored rectangles. There is one rectangle for each demographic group for each treatment arm. The area of each rectangle is proportional to the proportions of each demographic group in each treatment arm.

Options

This panel enables you to select the demographic variables used to create distributions, specify the number of decimal places to display and perform treatment comparison analysis for the demographic groups.

Create additional distributions for selected variables

This option enables you to add or remove demographic variables from DM from the distributions.

8 Click to open the Add window shown below:

8 Select one or more variables and click
8 To remove one or more distributions, highlight the variables to be deleted and click .
8 To rearrange the order of the distributions, select a variable and click either or .

Number of Decimals to Display for Numeric Results

Use this option to specify the number of decimals to include in the plots and tables of numerical results.

Perform treatment comparison analysis for demographic variables

Check this box to generate the treatment comparisons shown above.

General and Drill Down Buttons

Action buttons, provide you with an easy way to drill down into your data. The following action buttons are generated by this report:

• Click to rerun the report using default settings.
• Click to view the associated data tables. Refer to Show Tables/View Data for more information.
• Click to generate a standardized pdf- or rtf-formatted report containing the plots and charts of selected sections.
• Click to generate a JMP Live report. Refer to Create Live Report for more information.
• Click to take notes, and store them in a central location. Refer to Add Notes for more information.
• Click to read user-generated notes. Refer to View Notes for more information.
• Click to open and view the Review Subject Filter.
• Click to specify Derived Population Flags that enable you to divided the subject population into two distinct groups based on whether they meet very specific criteria.

Default Settings

Refer to Set Study Preferences for default Subject Level settings.

Methodology

No testing is performed. Analysis is restricted to tabulating counts/percentages of subjects' demographic data.