Uniques Occurrence Subject Counts

This drill down is useful when the AE Distribution report dialog option to Count multiple occurrences of an event per subject is checked.

The resulting dashboard then shows all event records (including records for the same AE that may have occurred multiple times for a given subject). Once that report is generated, the user can select certain criteria for given Adverse Events either interactively or through the JMP data filter shown on the report dashboard. This action button can then be run to consider the selected/filtered AE records only and take the FIRST OCCURRENCE for each subject per each adverse event.

This allows you to create a subject count representation of AE occurrence based on any general criteria.

For example: When the Count multiple occurrences of an event per subject dialog check box is UNCHECKED, the software automatically picks representative subject event records based on the most SERIOUS (AESER = Y), SEVER (AESEV), and then first occurring. This way, the descriptive quality of the AE occurrence selected to be representative of each subject is likely the most notable.

Instead, if you CHECK the box for count multiple occurrences, then you can make an arbitrary filter (e.g. all MILD events) and use this action button to get a representative count of all subjects that experienced a given (e.g. MILD) AE. These numbers would not have been reflected if one of those same subjects also experienced a SEVER event as well as a MILD given event.