Note: JMP Clinical uses a special protocol for data including non-unique Findings test names. Refer to How does JMP Clinical handle non-unique Findings test names? for more information.
Running this report with the Nicardipine sample setting generates the report shown below.
The Report contains the following elements:
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Outliers Volcano Plot: Shows a volcano plot used to determine the deviation of the proportion of outliers at each study site with the overall proportions for the whole study. The x-axis is calculated using p(site) - p(reference), where p(site) is the proportion (or percent)of outliers in the site in question and p(reference) is the proportion of outliers in all other sites.
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ECG Test Results (Outliers): Displays histograms showing distribution of ECG findings across study sites, tests, and visit numbers, as well as the frequencies and types of outliers.
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Laboratory Test Results (Outliers): Displays histograms showing distribution of laboratory test findings across study sites, tests, and visit numbers, as well as the frequencies and types of outliers.
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Vital Signs (Outliers): Displays histograms showing distribution of vital signs findings across study sites, tests, and visit numbers, as well as the frequencies and types of outliers.
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Show Sites: Shows the rows of the data table for the selected points from the volcano plot. Clicking
 opens the following table: |
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Frequencies Barcharts: Select points on the volcano plot and click
 to display a bar chart for each point showing the proportions of outliers for the site as compared with the average of all of the other sites. |
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Profile Subjects: Select subjects and click
 to generate the patient profiles. See Profile Subjects for additional information. |
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Show Subjects: Select subjects and click
 to open the ADSL (or DM if ADSL is unavailable) of selected subjects. |
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Click
 to view the associated data tables. Refer to View Data for more information. Note: Numeric data for individual subjects come directly from the xxSTRESN1 variable from the domain data sets. |
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Click
 to generate a standardized pdf- or rtf-formatted report containing the plots and charts of selected sections. |
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Click
 to take notes, and store them in a central location. Refer to Add Notes for more information. |
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Click
 to read user-generated notes. Refer to View Notes for more information. |
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Click the arrow to reopen the completed report dialog used to generate this output.
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Click the gray border to the left of the Options tab to open a dynamic report navigator that lists all of the reports in the review. Refer to Report Navigator for more information.
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This report compares the outlier status of tests with each site compared to all other sites taken together as a reference. A point is an outlier if it exceeds the upper outlier limit (Q3+1.5×IQR) or is less than the lower outlier limit (Q1-1.5×IQR), where Q1 and Q3 are first and third quartiles and IQR =Q3-Q1. It then compares the rate of outliers using Fisher's exact test. FDR p-values are calculated and the reference line is determined as described in How does JMP Clinical calculate the False Discovery Rate (FDR)?.
Where xx is the two-letter domain name.