Report Output | Overviews | Missing Findings

Missing Findings
This report determines whether individuals are missing data for all test codes across all Findings domains, based on data available at each visit number and time point number.
Note: JMP Clinical uses a special protocol for data including non-unique Findings test names. Refer to How does JMP Clinical handle non-unique Findings test names? for more information.
Running Missing Findings for the Nicardipine study using default settings generates the report shown below:
This report contains the following elements:
Missing Findings Volcano Plot: Shows a volcano plot used to determine the deviation of the proportion of missing fundings results at each study site with the overall proportions for the whole study.
ECG Test Results (Missing Findings): Displays histograms showing distribution of ECG findings across study sites, tests, and visit numbers, as well as the frequencies of records with either available or missing results. Note: This test is usually not performed at every visit and so is normally not considered in this analysis. To view missing ECG results, you must reduce the threshold percentage of expected subjects and rerun the report.
Laboratory Test Results: Displays histograms showing distribution of laboratory test findings across study sites, tests, and visit numbers, as well as the frequencies of records with either available or missing results. Note: This test is usually not performed at every visit and so is normally not considered in this analysis. To view missing ECG results, you must reduce the threshold percentage of expected subjects and rerun the report.
Vital Signs (Missing Findings): Displays histograms showing distribution of vital signs findings across study sites, tests, and visit numbers, as well as the frequencies of records with either available or missing results.
Down Buttons
down buttons, provide you with an easy way to down into your data. The following down buttons are generated by this report:
Show Sites: Shows the rows of the data table for the selected points from the volcano plot. Clicking opens the following table:
Missing Bar Charts: Select points on the volcano plot and click to display a bar chart for each point showing the proportions of missing and nonmissing records for the site as compared with the average of all of the other sites.
Profile Subjects: Select subjects and click to generate the patient profiles. See Profile Subjects for additional information.
Show Subjects: Select subjects and click to open the ADSL (or DM if ADSL is unavailable) of selected subjects.
Show Records with Missing Test Results: Select one or more histograms and click to open a subset table containing all of the missing tests for the selected subjects.
General
Click to generate a standardized pdf- or rtf-formatted report containing the plots and charts of selected sections.
Click to read user-generated notes. Refer to View Notes for more information.
Click the Options arrow to reopen the completed report dialog used to generate this output.
Click the gray border to the left of the Options tab to open a dynamic report navigator that lists all of the reports in the review. Refer to Report Navigator for more information.
Methodology
This report determines whether tests are expected or not at each visit according to dialog option (default 85%). If 85% of patients at a particular visit and/or time point have a test measured, this test is expected (assuming that the subjects have had the opportunity to attend this visit). Among expected tests and for each test, the proportion of “missingness” is calculated for each site (the suspect site, indexed with s) compared to all other sites taken together as a reference (indexed as o) using a Fisher's exact test. FDR p-values are calculated and the reference line is determined as described in How does JMP Clinical calculate the False Discovery Rate (FDR)?.