By default, framework markers specified in the Framework Linkage Group Variable field on either the
Annotation or
Framework Map tabs are not included in the
k-means clustering analysis to filter representative markers. By default, any framework marker is assumed to be a representative marker and is output among representative markers from the
k-means clustering analysis of non-framework markers.
Note: When this option is checked, the Framework Linkage Group Variable is used as a
variable in the BY statement of the SAS/STAT PROC FASTCLUS procedure, and clustering analysis is carried out within each level of this
variable.