Expanded Genotype Recoding

Use this feature to specify whether to use numeric additive coding or dominant coding when converting to expanded genotypes.

Available options are described in the following table:

Test	Description
Numeric Additive (2 1 0)	To convert genotypes to values representing whether or nor a specific allele is present in one or two copies. A separate column is generated for each marker allele and populated with numeric genotypes corresponding to the number of specified alleles in the genotype. For example, if Marker1 has three alleles (A, B, and C) three columns (Marker1_A, Marker1_B, and Marker1_C) are generated. In column Marker1_A, individuals with two copies of A at Marker1 (A/A homozygotes) are denoted with a “2”. Individuals with one copy of A (A/B and A/C heterozygotes) are denoted with a “1”. Individuals with no copies of A (B/B and C/C homozygotes and B/C heterozygotes) are denoted with a “0”. The Marker1_B and Marker1_C columns are coded for alleles B and C in a similar fashion.
Numeric Dominant (1 1 0)	To convert genotypes to values representing whether or not a specific allele is present. A separate column is generated for each marker allele and populated with numeric genotypes corresponding to the presence or absence of specified alleles in the genotype. For example, if Marker1 has three alleles (A, B, and C) three columns (Marker1_A, Marker1_B, and Marker1_C) are generated. In column Marker1_A, individuals with at least one copy of A at Marker1 (A/A homozygotes or A/B or A/C heterozygotes) are denoted with a “1”. Individuals with no copies of A (B/B and C/C homozygotes and B/C heterozygotes) are denoted with a “0”. The Marker1_B and Marker1_C columns are coded for alleles B and C in a similar fashion.

Test

Description

Numeric Additive (2 1 0)

To convert genotypes to values representing whether or nor a specific allele is present in one or two copies.

A separate column is generated for each marker allele and populated with numeric genotypes corresponding to the number of specified alleles in the genotype.

For example, if Marker1 has three alleles (A, B, and C) three columns (Marker1_A, Marker1_B, and Marker1_C) are generated. In column Marker1_A, individuals with two copies of A at Marker1 (A/A homozygotes) are denoted with a “2”. Individuals with one copy of A (A/B and A/C heterozygotes) are denoted with a “1”. Individuals with no copies of A (B/B and C/C homozygotes and B/C heterozygotes) are denoted with a “0”. The Marker1_B and Marker1_C columns are coded for alleles B and C in a similar fashion.

Numeric Dominant (1 1 0)

To convert genotypes to values representing whether or not a specific allele is present.

A separate column is generated for each marker allele and populated with numeric genotypes corresponding to the presence or absence of specified alleles in the genotype.

For example, if Marker1 has three alleles (A, B, and C) three columns (Marker1_A, Marker1_B, and Marker1_C) are generated. In column Marker1_A, individuals with at least one copy of A at Marker1 (A/A homozygotes or A/B or A/C heterozygotes) are denoted with a “1”. Individuals with no copies of A (B/B and C/C homozygotes and B/C heterozygotes) are denoted with a “0”. The Marker1_B and Marker1_C columns are coded for alleles B and C in a similar fashion.

To Specify This Option:

Click the desired radio button.