Normalize copy number data using autosomes
Check this option to perform a two-step normalization on copy number intensity data:
• | First, the observations from non-autosomes (X and Y) are separated from autosomes. |
• | The normalization is then applied only to autosome data. |
• | For each observation from non-autosomes, normalized data from the nearest smaller and nearest larger autosomes are interpolated. |
Note: Checking this box disables the parameters corresponding to Baseline Reference for quantile normalization.
To Normalize Copy Number Data Using Non-autosomes:
8 | Check the box. |