The
K
setting determines which partitions have a Minor Arc: a segment with at most
K
chromosome
positions. A Minor Arc
p-value
is computed from partitions found from Monte Carlo permutations. Large values of
K
decrease the
power
of the test, increase search time by
K
-squared, but render the Major Arc
p
-values a better fit to the asymptotic formula.
Tip
:
K
is recommended to be
25
or greater, typically
100
at most. Increasing
K
warrants increasing the number of permutations.
