Check this box to calculate the absolute value of the
experimental - control
intensity (or count) subtraction. This option is ideal for LOH (
loss of heterozygosity
) analysis. For example, this option is useful when there is an interest to determine whether the
genotype
count changed from
heterozygous
in the normal
tissue
sample to
homozygous
for either the dominant or the recessive
allele
in the tumor tissue sample.
