A pyridoxal phosphate-dependent transaminase enzyme, also known as aspartate aminotransferase (AspAT, ASAT, AAT) or serum glutamic oxaloacetic transaminase (SGOT). Catalyzing a reversible transfer between aspartate and glutamate, it is found in the brain, heart, muscles, kidneys, red blood cells, and liver. It is a clinical diagnostic indicator of liver health.