Running this process using the Example sample setting generates the tabbed Results window shown below. Refer to the Survey SNP-Trait Association process description for more information. Output from the process is organized into tabs. Each tab contains one or more plots, data panels, data filters, and so on. that facilitate your analysis.
The Results window contains the following panes:
This pane provides you with a space to view individual tabs within the Results window. Use the tabs to access and view the output plots and associated data sets.
The following tabs are generated by this process, depending on the parameters specified on the process dialog:
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Summary Chart: When there are multiple annotation groups (chromosomes or genes, for example), this tab displays the number of significant markers in each annotation group for each test. Separate bar charts are shown for each BY group when any By Variables are specified. This tab is open by default.
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Manhattan Plot: When there are multiple annotation groups (chromosomes or genes, for example), this tab displays a scatter plot of the p-values across all annotation groups.
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Annotation Group Results: When there are multiple annotation groups (chromosomes or genes, for example), a separate Results tab with an overlay plot of p-value by chromosome location is created for each annotation group. If the Calculate trend odds ratios check box was checked, this tab also contains a Volcano Plot of p-value by log odds ratio for all markers.
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All P-Value Plots: When there are multiple annotation groups (chromosomes or genes, for example), the All P-Value Plots tab shows all the p-value plots from the Annotation Group Results tabs in a single display.
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Note: When an annotation group variable is not specified or there is only one annotation group, the tab is named P-Value Plot and contains an overlay plot of p-value by chromosome location for all markers.
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All Trends Odds Ratio Plots: : If the Calculate trend odds ratios check box was checked and there are multiple annotation groups (chromosomes or genes, for example), this tab shows all the odds ratio volcano plots. If the Calculate trend odds ratios check box was checked and an annotation group variable is not specified or there is only one annotation group, the tab is named Trend Odds Ratio Plot and contains an overlay plot of p-value by log odds ratio for all markers.
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Volcano Plot(s) (Survey SNP-Trait Association): This tab displays a scatter plot of p-value by the Estimate of Minor Allele Genotype Effect for all markers, colored by Annotation Group, when the trend test is performed. .
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SAS Output: This tab, which is generated when the List every model fit check box is checked, displays the SAS output from the SAS survey procedure that is used to calculate test statistics for the model: SURVEYREG for a continuous trait, SURVEYLOGISTIC for a non-continuous trait, and SURVEYFREQ for the Rao-Scott tests for a non-continuous trait.
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GenBank Nucleotide: Select points or rows and click to opens a browser window directed to a GenBank Nucleotide search for the selected molecular entities.
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UniGene Database: Select points or rows and click to access information from the Unigene database for selected genes or markers
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AceView Database: Select points or rows and click to access information from the ACEView database for selected genes or markers.
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View Venn Diagram of Significant Markers by Trait for the Test Below: Click either or to view a Venn diagram showing significant association between markers and multiple traits as determined by the specific association test.
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Note: This option is available only when two or more Trait Variables are specified.
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Create Subset Genotype and Annotation Data Sets: Select points from the p-value plots and click to open the Subset and Reorder Genetic Data process to create the subset data sets.
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Plot Trait by Genotype: Select markers from the p-value plots and click to view each marker's genotype distribution for each of the Trait Variables values.
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Note: This action button is available only when numeric genotypes are specified.
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Genotype Parameter Estimate Data Set: This data set contains the estimates and test statistics for the fixed effects included in each regression model testing for association, including the marker genotype treated as a categorical variable, and is generated when the Genotype test is performed. The name of this data is set is given by the Output File Prefix, or input data set name if none given, with the suffix _peg. Click to view the data set.
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Trend Parameter Estimate Data Set: This data set contains the estimates and test statistics for the fixed effects included in each regression model testing for association, including the numeric marker genotype treated as a continuous variable, and is generated when the Trend test is performed. The name of this data is set is given by the Output File Prefix, or input data set name if none given, with the suffix _pet. Click to view the data set.
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P-value Data Set: This data set contains all the columns from the annotation data set, plus the test statistics and p-values from the tests performed. This data set can be used as the annotation data set for subsequent processes to accumulate results from multiple processes into a single data set. The name of this data is set is given by the Output File Prefix, or input data set name if none given, with the suffix _sst. Click to view the data set..
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For detailed information about the files and data sets used or created by JMP Life Sciences software, see Files and Data Sets.
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Click to reveal the underlying data table associated with the current tab.
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Click to reopen the completed process dialog used to generate this output.
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Click to close all graphics windows and underlying data sets associated with the output.
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