Probe Normalization Method

Specify a method for normalization.

Note: The options that you see might differ from those shown or described.

Methods are described below.

Method	Description
None	No normalization is performed.
Mean Scaling	Shift the data of each array to have the same mean, which is defaulted to zero.
Median Scaling	Shift the data of each array to have the same median, which is defaulted to zero.
Quantile	Normalizes the data by quantile normalization. The kernel parameters are set to the same as default in the Quantile Normalization process. If you want to perform quantile normalization using different parameters, open the Quantile Normalization process under Expression > Normalization.
Loess	Normalizes the data by loess normalization. The smoothing parameter, kernel parameters, and number of loess iterations are set to the same as default in the Loess Normalization process. If you want to perform loess normalization using different parameters, please open the Loess Model Normalization process under Expression > Normalization.
MAT	Performs model-based analysis of tiling arrays for detection of regions binding probes containing sequences enriched for transcription factor binding sites. (Johnson et al., PNAS, 2006).

To Specify a Probe Normalization Method:

Click the radio button corresponding to the desired method.