1.
Select DOE > Classical > Screening Design.
2.
Double-click Y under Response Name and type Yield.
3.
Select Load Factors From the red triangle next to Definitive Screening Design.
4.
Open the Extraction Factors.jmp sample data table, located in the Design Experiment folder.
5.
Click Continue.
6.
Select Choose from a list of fractional factorial designs.
7.
Click Continue.
Screening Design List for Six Continuous Factors
9.
Click Continue.
10.
Open the Display and Modify Design > Aliasing of Effects outline.
Aliasing of Effects for Fractional Factorial Design
The Aliasing of Effects outline for the 16-run fractional factorial design shows that every two-factor interaction is confounded with at least one other two-factor interaction. In this fractional factorial design, the Ethanol*Time interaction is confounded with Methanol*pH. To determine which interaction is active, you need to run additional trials. If the factors had been entered in a different order, the Ethanol*Time interaction might have been aliased with two other two-factor interactions.
In the section Definitive Screening Design, you constructed a 17-run definitive screening design. The Color Map on Correlations for this DSD (Color Map on Correlations for Extraction Design) shows that no two-factor interactions are confounded with any other two-factor interactions. For the fractional factorial design, there are seven instances of confounded two-factor interactions. If you suspect that there are active two-factor effects, the DSD is the better choice.

Help created on 9/19/2017